We studied syntopic populations of white-footed mice (Peromyscus leucopus) and deer mice (P. maniculatus) in mid-successional vegetation to determine microhabitat selections on experimental plots in northeastern Kansas. Microhabitat selections, based on woody stem densities (WSD), differed between species and differed from expected for both species. Peromyscus leucopus used habitats with medium and high WDS more than expected, whereas P. maniculatus used habitats with low WSD more than expected. Our results indicate that as plant succession proceeds on experimental plots, habitats preferred by P. leucopus should increase, whereas habitats preferred by P. maniculatus should decrease.